Cell Wall Biosynthesis
We are interested in the structure & assembly of cell surface polymers that form extracellular architectures. Many organisms extend their surfaces as protective barriers, to mediate cellular interactions, and to confer mechanical strength.
Our research focuses on complex carbohydrates and how they are synthesized and deposited on the cell surface. Using the tools of structural and molecular biology, we study capsule and biofilm formation in bacteria, cell wall biosynthesis in plants, and extracellular matrix formation in vertebrates.