Recent Publications

  1. Structure, substrate recognition and initiation of hyaluronan synthase, Maloney, FP#, Kuklewicz, J.#, Corey, RA., Bi, Y., Ho, R., Mateusiak, L., Pardon, E., Steyaert, J., Stansfeld, PJ., Zimmer, J., Nature 2022 Apr;604(7904):195-201

  2. Molecular organization of the E. coli cellulose synthase macrocomplex, Acheson, J., Ho, R., Goularte, N, Cegelksi, J, Zimmer, J., Nat Struct Mol Biol. 2021 Mar;28(3):310-318

  3. Cryo-EM structure of the full-length WzmWzt ABC transporter required for lipid-linked O antigen transport, Caffalette, C. and Zimmer, J., Proc Natl Acad Sci U S A. 2021 Jan 5;118(1)

  4. Architecture of a catalytically active homotrimeric plant cellulose synthase complex, Purushotham, P., Ho, R., Zimmer, J., Science 2020 Aug 28;369(6507):1089-1094
  5. A lipid gating mechanism for the channel-forming O antigen ABC transporter, Caffalette, C., Corey, R., Sansom, M., Stansfeld, P., Zimmer, J., Nature Commun. 2019 Feb 18;10(1):824
  6. Architecture of a channel-forming O-antigen polysaccharide ABC transporter, Bi, Y., Mann, E., Whitfield, C., Zimmer, J., Nature. 2018 Jan 18;553(7688):361-365
  7. Distinct reaction mechanisms for hyaluronan biosynthesis in different kingdoms of life, Blackburn, M., Hubbard, C., Kiessling, V., Kloss, B., Tamm, L., Zimmer, J., Glycobiology. 2018 Feb 1;28(2):108-121
  8. Structure of a Type-1 Secretion System ABC Transporter, Morgan, JL., Acheson, J., Zimmer, J., Structure. 2017 Mar 7;25(3):522-529
  9. Observing cellulose biosynthesis and membrane translocation in crystallo, McNamara JT, Morgan JL, Fischer M, Rich J, Chen HM, Withers S, Zimmer J., Nature. 2016 Mar 17;531(7594):329-34
  10. A single heterologously expressed plant cellulose synthase isoform is sufficient for cellulose microfibril formation in vitro, Purushotham, P., Cho, S., Diaz-Moreno, S., Kumar, M., Nixon, T., Bulone, V., Zimmer, J., Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11360-11365
  11. A molecular description of cellulose biosynthesis, McNamara JT, Morgan JL, Zimmer J., Annu Rev Biochem. 2015, 84:895-921
  12. Mechanism of activation of bacterial cellulose synthase by cyclic di-GMP, Morgan, JL, McNamara, JT, Zimmer J., NSMB. 2014, May;21(5):489-96.
  13. Crystallographic snapshot of cellulose synthesis and membrane translocation, Morgan JL, Strumillo J, Zimmer J., Nature 2013, 493, 181-6
  14. The hyaluronan synthase catalyzes the synthesis and membrane translocation of hyaluronan, Hubbard C, McNamara JT, Azumaya C, Patel MS, Zimmer J., J Mol. Biol. 2012, Apr 20;418(1-2):21-31
  15. BcsA and BcsB form the catalytically active core of bacterial cellulose synthase sufficient for in vitro cellulose synthesis, Omadjela O, Narahari A, Strumillo J, Mélida H, Mazur O, Bulone V, Zimmer J., Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17856-61.

A complete list of our publications can be found here.